Ghost in the Shell and Mushishi. My exposure to non-anime mediums is a bit limited.

I enjoy Greed. The nice thing about him is that while his history is dynamically modified into a major cornerstone of the anime-only plot, his personality is 100% intact across both canons. The problem of whether or not someone can apply for manga Greed and NOT take Ling, thus cutting off any potential Ling's options is all someone else's problem~~